The extract also made the mouses fur glossier and improved bowel movement regularity. One recent clinical study published in the Journal of Clinical Oncologyshowed that this MCP effectively slowed PSA doubling time and cancer progression in patients with biochemical relapse of prostate cancer. Their sole purpose is to help you survive by stimulating fight or flight action. During the 7th century, monks in the Chinese Buddhist temples grew these trees in their gardens for use in treating conditions like depression, asthma, muscle pain, and headache. Researchers attributed these effects to honokiols potential to reduce anxiety and stress. And part of that means better understanding galectin-3. It confuses your immune system so much that it triggers immune overreactions and under-reactions. This is why I use meditation as an integral part of my medical and healing practice. It was said to treat "fright qi" a condition caused by emotional distress due to fear and anxiety.. Thor needed a miracle to survive. Use a combination of these stress-reducing methods to calm down your mind and body no matter what life throws at you. The magnolia extract improved health issues such as anxiety, insomnia, depression, and libido. Thats why you probably feel sick when youre stressed out. In order to stay ahead of the disease, we have to outwit it at every turn. No adverse effects related to magnolia bark or the compounds it contains have been observed. The more effectively you cope with stress today, the healthier youll be for the rest of your life. Later, it was described in many famous Chinese medical texts such as the "Jingui Yaolue" and the "Shanghan Lun" (ca. Researchers ensured that there was a steady dose of honokiol throughout the study (while the other ingredients varied) in order to confirm their hypothesis. This is why its best to speak with your healthcare provider before taking magnolia bark alone or in combination with other supplements and medications. The calming effects are unlike anything we have come across and produce a very comprehensive effect. If you decide to take magnolia bark, carefully read the manufacturers instructions to know how much to take and how often. In a 2022 study, a supplement containing magnolia bark and phellodendron bark (Phellodendron amurense) was used to reduce stress and cortisol levels in 56 moderately-stressed participants. are clickable links to medically peer-reviewed studies. Multiple published papers on this unique extract demonstrate its effectiveness and safety, including one study showing it works synergistically with MCP. Moreover, studies in both test tubes and living organisms have demonstrated that magnolia bark extract has no mutagenic or genotoxic properties, meaning theres a low risk of magnolia bark causing genetic mutations (1). The soy isoflavones were more effective for hot flashes, vaginal dryness, nocturnal sweating, and palpitations [R, R]. Honokiol, a putative anxiolytic agent extracted from magnolia bark, has no diazepam-like side-effects in mice. Currently, there are no official recommendations for magnolia bark dosage. Magnolia seems to have. And its free! You may feel more worried, snap more easily, or have bigger emotional reactions than would normally match the situation youre in. The combination was tested against an independent honokiol dose and an independent radiation dose. In a mouse study, honokiol proved to elicit the anxiolytic effect in Hange-koboku-to and Saiboku-to, two medicines used in traditional Chinese medicine and Kampo (traditional Japanese medicine). The health of the digestive system is important because it controls how your body processes and eliminates the food that you consume. The Physiomedical Dispensatory. It is the most effective treatment I know. And when you pair honokiol with MCP, the antioxidant and anti-inflammatory effects of both increase significantly, offering more stress relief for you. Magnolia bark is a popular herb in traditional Chinese and Japanese medicine. With strict editorial sourcing guidelines, we only link to academic research institutions, reputable media sites and, when research is available, medically peer-reviewed studies. 9. Galectin-3 allows tumor cells to stick together, develop blood supply, metastasize and evade the immune system. Science. So how exactly do we solve this paradox? (2017). Information on this website is provided for informational purposes only and is not intended as a substitute for the advice provided by your physician or other healthcare professional. In a preventative animal study, magnolia barks active constituent, honokiol, was able to prevent the development of skin cancer. | Henriette's Herbal Homepage. Nevertheless, additional research in humans is needed. Magnolol inhibited cancer growth and reduced tumor size in vitro. biloba fruits and their protective effects against free radical-induced oxidative damage. Both the root and branch bark are used in therapeutic medicine. This advanced blood filtration treatment reduces inflammatory compounds and growth factors, as well as galectin-3, and can significantly change the outcome of cancer treatment. Modern research shows that magnolia bark has anti-inflammatory, antioxidant, stress, and weight-reducing effects. So go for a walk, take a bike ride, or dance around the room and let those endorphins kick in. A 24-week study in 89 menopausal women experiencing symptoms of sleep and mood alterations were given a supplement containing 60 mg of magnolia bark extract and 50 mg of magnesium daily. In this article, we will look at the health benefits of magnolia bark, its safety, and its history. It produces mature red, conelike fruit from September through October when it opens up to display its seeds. Along with increasing your overall resilience, MCP blocks galectin-3, the alarm protein that triggers inflammation and causes many of the harmful effects associated with chronic stress. A second study in mice observed similar outcomes after administering honokiol, which also decreased the amount of time it took the mice to fall asleep and transition into non-REM sleep (28). Magnolia bark has a sedative effect on the body and has been used to promote sleep and ease anxiety. Other purported magnolia bark benefits include: While these various other health benefits of magnolia bark are interesting, human clinical trials are needed to corroborate these findings. As mentioned, magnolia bark extract appears to have protective effects against many neurological conditions. BARC is specifically aimed at helping pets live longer, healthier lives by treating them using a holistic approach combining both Eastern . Though the use of magnolia bark is common in traditional Chinese medicine, you may wonder what current research says about the tree bark. https://doi.org/10.3748/wjg.v11.i28.4414, Zhang, Y. J., Li, S., Gan, R. Y., Zhou, T., Xu, D. P., & Li, H. B. When youre constantly stressed out, it feels much harder to think clearly. This Dr. Axe content is medically reviewed or fact checked to ensure factually accurate information. In Kampo or traditional Japanese medicine, magnolia bark was also used for gastrointestinal support. Research shows that both magnolol and honokiol are, by nature: The extract of the magnolia bark has been used for thousands of years in traditional Chinese and Japanese medicine. As an integrative MD and researcher, licensed acupuncturist and life-long practitioner of Buddhist meditation, Ive developed a unique perspective and methodology around mind-body medicine, and specifically, our innate abilities to heal ourselves and others. A., & Pugh, M. (2013). One type Magnolia officinalis is commonly called the houpo magnolia, or sometimes simply magnolia bark.. https://doi.org/10.1631/jzus.B1600299, Qu, W. M., Yue, X. F., Sun, Y., Fan, K., Chen, C. R., Hou, Y. P., Urade, Y., & Huang, Z. L. (2012). Go for a walk in the woods, dip your feet in the ocean, or relax on a hammock in your backyard. Exceeding the recommended daily limit of magnesium can lead to diarrhea, nausea, stomach cramps, and heart problems. Doing so may cause drowsiness and make it unsafe for you to drive or use heavy machinery., Alternative Therapies in Health and Medicine: Effect of a proprietary Magnolia and Phellodendron extract on weight management: a pilot, double-blind, placebo-controlled clinical trial., Current Microbiology: The Therapeutic Effects ofMagnolia Officinalis Extraction on an Antibiotics-Induced Intestinal Dysbacteriosis in Mice., Institute for Traditional Medicine: MAGNOLIA BARK., Journal of the International Society of Sports Nutrition: Effect ofMagnolia officinalis andPhellodendron amurense (Relora) on cortisol and psychological mood state in moderately stressed subjects., Journal of Zhejiang University. Many benefits of magnolia bark can be attributed to two powerful polyphenols magnolol and honokiol. The symptoms associated with this condition mimic closely the westernized definition of "burnout". This dried bark known for its sharp smell and bitter taste is then soaked in a traditional medicine tincture for oral use. Futurebiotics Ashwagandha Capsules Extra Strength 3000mg - Stress Relief Formula, Natural Mood Support, Stress, Focus, and Energy . The information in our articles is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It should be noted that while anxiety was temporarily reduced, there was no long-term effect after participants stopped using the blend. Our website content is for informational purposes only. Some researchers believe that these effects are due to honokiol, a natural compound in the bark. The researchers found that the isoflavones effectively lessened the severity of classic menopausal symptoms, including hot flashes, while magnolia bark eased the participants anxiety. Effect of Magnolia officinalis and Phellodendron amurense (Relora) on cortisol and psychological mood state in moderately stressed subjects. The Medical journal of Australia, 199(S6), S28S31. In vitro and animal data. Honokiol: When stress and anxiety overwhelm your mind and your life, honokiol a compound extracted from magnolia bark offers quick, calming relief. British journal of pharmacology, 167(3), 587598. https://doi.org/10.1021/np800494e, Siegel, R. L., Miller, K. D., & Jemal, A. Thats because chronic stress keeps the brain flooded with high levels of cortisol the stress hormone and that can interfere with optimal brain function. It should be noted that results improved when dose size increased. But when you face stressors all the time work deadlines, traffic jams, bad news the system cant turn off. Honokiol was able to prevent cell growth while inducing cancer cell death. When taken together, the evidence conveys that magnolia bark extract may help with the psycho-affective symptoms of menopause. Research shows that a number of healthy stress relief strategies, including those listed below, also offer protection against Alzheimers and other forms of cognitive decline. Thousands of published studies show how galectin-3, an adhesive cell surface protein with roles in cellular development and injury repair, acts as the number one driver of cancer progression and metastasis, as well as the initial alarm that controls the biochemical response to fight or flight survival. The supplement can not only help improve sleep, stress, anxiety, and symptoms of menopause but also may have anticancer and antioxidant properties. My mission is to provide a holistic approach to health and wellness, and bringing balance to the min All of this makes it all the more important to explore natural ways to relieve stress. It Starts in the Kitchen, Acid Reflux Diet: Best Foods, Foods to Avoid & Supplements that Help, Black Mold Symptoms + 12 Natural Remedies, Traditional Chinese Medicine Benefits, Herbs & Therapies, Chronic low-level inflammation, which can be triggered by high levels of a, Difficulty learning and retaining new information. Dosage Examine Database Magnolia officinalis, also known as magnolia bark, has been widely used in traditional Chinese medicine and has many benefits. The women experienced significant improvements in insomnia, anxiety, mood, and irritability (31). Stress relief for you evidence conveys that magnolia bark extract may help the... Effectively you cope with stress today, the healthier youll be for the rest of your.. Feels much harder to think clearly wonder what current research says about tree..., bad news the system cant turn off been observed no matter what throws! 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