Item Pool: Devil Room, Curse Room, Red Chest, Super Pride Miniboss, * curse room pool, red chest pool, red chest item pool, devil pool, devil room pool, devil deal. Has a chance to drop while playing any Blood Donation machine. *, the lost item pool, silver, metal, grey, gray. Tears are replaced with a knife which can be charged and thrown in a boomerang style action. Tears Down significantly (Tear delay * 2.1 + 3). *, red, grey, gray, brown, black, red, eyes. - Spawns one blue attack spider for every enemy in the room. Identical to the standard Red Heart, but will run away as the player moves towards it. Possible mushrooms include: Mini Mush, Odd Mushroom (Thin), Odd Mushroom (Thick), The Compass. A bag that floats around following Isaac and drops a random coin every 2 rooms. Spoon Bender, Telepathy for Dummies, I - The Magician). Doubles your current red hearts up to full health. Bombs will also synergize with other bomb items and tear modifiers, including Sad Bombs, Mr. Mega and many more. Tears can now be charged and released in a shotgun style effect, much like Monstro's main attack. In larger rooms, Abel will mirror to the other side of the screen instead of the entire room. Its costume no longer overwrites the player's skin color to pink instead of white. * curse room pool, demon beggar pool, demon judgement pool, devil beggar pool, devil pool, Gives Isaac a full mapping effect, revealing the entire floor and locations of all secret rooms. Gives Isaac high damage tears with a short range. A random chance when you take damage to get an invincibility shield for 7 seconds. UNLOCK: Unlock this item by beating ??? An item only found in the boss room pool. * item room, treasure room, item room pool, chop, head, silver, metal. Upon use, creates a stationary sprinkler that rotates and fires tears in 8 directions. For the Lost and Keeper characters, this item simply gives a permanent Tears Up. * Shop, Greed Mode Item Room, white, blue, inhaler. Heals half a heart after every 13 enemies killed. Item Pool: Item Room, Greed Mode Item Room, Beggar. Added as part of the Afterbirth+ Booster Pack #5. * library pool, library room, book room pool, devil pool, devil room pool, devil deal, starting [better source needed] Succubus, a horror action video games by Madmind Studio, a demon princess, Vydija, as a playable character. After a few seconds, the crosshair will disappear, and the Ghost will do certain things based on what you targeted: Items, pickups, trinkets: Brings them to Isaac. This familiar is very similar to Incubus, however it only copies damage and is not affected by tears or range upgrades. UNLOCK: Unlock this card by beating Challenge #22 (Speed). UNLOCK: Unlock this item by beating Blue Womb (Hush) with Azazel. Pre-Afterbirth this dealt 4 or 6 damage, instead of scaling with your tear damage. Spoon Bender will give them a homing effect), Tears which fall naturally to the floor at max range do not generate sparks. Gives you extra stat upgrades based on the items you've already collected that have stat increases, at +33% of the item's original increase, Also gives you a +0.2 Tears Up and -1 Tear Delay even if you don't have an item that increases your tears stat. * item room, treasure room, item room pool, yellow, smile, face, bug. As well as dealing the standard 60 damage for a bomb, it will apply a Damage over Time effect that does 4 or 6 damage per tick. Cube of Meat after defeating a Horseman. During the delay when transitioning between rooms, picking up an item, or using an active item, it's possible to change firing direction without resetting the bonus. Holding Rib of Greed increase your chance to receive coin drops. The chance to fear enemies is affected by your luck stat and at +85 Luck it will activate every time. A throwable active item that places a black hole on the ground where it lands, sucking all enemies into it for 6 seconds, Enemies stuck inside the black hole take rapid damage over time, The Black Hole will also suck Isaac into it, but with a much weaker effect than to enemies, The Black Hole will destroy nearby obstacles such as rocks and pots, Adds a random chance for an enemy in the current room to become charmed or feared briefly, Adds a random chance to spawn a rainbow poop upon taking damage, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Electoon. Has no recharge time and can be used as often as you like. Black: Does not attack with Pits or troll bombs, but fires smoke balls more frequently. *, stone, rock, grey, gray, white, dice, pip, broken, die. *, the lost item pool, pink, red, guts, intestine, tube. Cambion Conception cannot grant more than 4 familiars in total. Upon entering every 4th unexplored room, the Broken Watch will either slow down or speed up all enemies in the room. * slot machine, arcade machine, money, bill, cash, green, * boss rush pool, boss rush room, item room, treasure room, item room pool, grey, gray, x10. Allows you to store up a lot of tears in the air and release them all at once. All damage taken is reduced to half a heart. A familiar which follows Isaac and shoots lasers, similar to the Technology item. If the initial run was on normal difficulty, all victory laps will be on hard difficulty. Deals 40 damage to everything in the room when used. The effect of the Credit Card only lasts for the current room. But The Lost also unlocks some of the best and most fun items in the game and is needed to get the final achievement, True Platinum God. While held, this trinket gives Isaac a familiar that shoots piercing tears that deal 3.5 damage. Does not explode if it hits Isaac, however if it explodes on an enemy while Isaac is in range, he will take damage. Unlocked from the 'Dedication' achievement (participate in 31 dailies in a row), I'm Drowsy - Slows all enemies for the rest of the current room, I'm excited!!! Enemies can turn into poop even if they do not do contact damage, allowing you to apply the effect without taking damage. Has a partial Magneto effect and will attract coins, pulling them into Isaac from a distance. Plastics Recycling 2019. UNLOCK: Unlock this item by beating Boss Rush with Eden. When Daemon's Tail is held, most future Heart drop will be rerolled into something else, with a certain chance to be rerolled into a Black Heart. Trisagion tears deal roughly 33% of your usual tear damage, however due to the size of the holy flash it is likely to hit enemies multiple times, Trisagion tears cause no knockback on enemies and simply travel through them (piercing tears), Added as part of the Afterbirth+ Booster Pack #4. Changes all half red hearts into full hearts. The chance to poison enemies is affected by your luck stat and at +18 Luck it will activate every time. A baby that resembles a very cool orange with sunglasses. * golden chest pool, gold chest pool, item room, treasure room, item room pool, follower, everyone knows it's abel, brown, grey, gray, dead, head, grey, green. Teleport to the player's new position if it was changed by a boss such as. Dice Shard counts as a card and will be converted. A baby that resembles the main character from Sgt. Item Pool: Devil Room, Curse Room, Greed Mode Devil Room, *, grey, gray, silver, metal grabber, hand, robot. UNLOCK: Unlock this item by defeating Delirium in The Void floor with Samson. UNLOCK: Unlock this item by beating Blue Womb (Hush) with The Lost. While you're firing tears Hushy will stop moving, which allows you to keep it in one place. * item room, treasure room, item room pool, dice pip, starting, pink, red, cube. Chests now have a 50/50 chance to either pay out with extra consumables or nothing/an enemy. Each laser does damage equal to your current tear damage. A familiar that follows Isaac and blocks tears. In general if a card has a number of things, that thing is doubled. Prevents Isaac from taking any damage, but instead summons a familiar heart that follows you around. Purity will boost one of Isaac's stats depending on the colour of the aura around him. In Afterbirth this item synergises with Brimstone and Tech, allowing them to do more damage the further away the enemy is. Tears fired at the minimum possible charge do roughly 1/3 of your normal damage. *, yellow, golden, coin, cent, money, cash, sparkle. A one time use item that when used will explode all objects (i.e. Fixed item drops won't be replaced - e.g. UNLOCK: Unlock this item by beating Boss Rush with Maggy. Upon use, Isaac shoots an explosive tear with the Ipecac effect that always deals 200 damage. On pickup removes all of your red hearts and gives you 6 black hearts. Donating to a Donation Machine has a chance to heal Isaac for a full red heart or spawn a Beggar. The highest damage orbital in the game, dealing 225 damage per second. While held, tears move in a spiral pattern across the screen at high speed. Gives you a higher chance of eternal hearts. While this trinket is held you have a significantly lower chance to find spacebar/active items. UNLOCK: Unlock this item by destroying 10 tinted rocks. Items which cost 2 heart containers in a deal with the devil are reduced to only cost 1 heart. When the tears are released, they will fire off in the direction that Isaac was originally facing when it was created. * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, This item will take from your soul hearts first. Also consumes all pickups in the room and turns them into blue flies and spiders. * item room, treasure room, item room pool, poison, green, brown, bottle, jar, danger. When picking up a coin, you have a chance to automatically gain one more coin. You may see more or less than this on the Found HUD overlay, however this number varies based on your other damage increasing items. UNLOCK: Unlock this item by beating the Dark Room with Eden. Gives Isaac a higher chance to find bombs. UNLOCK: Unlock this item by beating Greed Mode with Lilith. Causes most familiars to deal double damage. In Afterbirth, taking multiple Steam Sales will reduce all shop prices to 0 coins. * secret room pool, devil pool, devil room pool, devil deal, silver, grey, gray, dig, spade, shovel, * shop room pool, shop item pool, item room, treasure room, item room pool, brown, pink. Removes the curse which is in effect on the current floor. Counts as 1 of 3 bum items needed towards the Super Bum transformation. Tears spawned from this item keep most effect that Isaac currently has applied to his tears. A familiar fly that can be moved around via use of the arrow keys dealing 2.5 contact damage per tick, similar to the Ludovico Technique's mechanic. Item Pool: Gold Chest, Greed Mode Gold Chest, Dead shopkeeper. When used, the D1 duplicates 1 random pickup in the current room, including cards, runes, chests and trinkets. hearts, keys, bombs, coins, pills, cards, trinkets etc. UNLOCK: Unlock this item by beating Challenge #29 (Onan's Streak). Isaac no longer takes damage from walking over spikes and blood creep while this trinket is held. When used this card will activate a use of your spacebar item for free. Changes all card and rune drops into pills. paper, roll, white. Gives Isaac the ability to fly and spectral tears. While held this trinket causes all pickups and enemies to move slowly towards you. Gives all bombs a burning effect when they explode, leaving fire on the floor which deals 22 damage to enemies. While firing tears constantly for 7.5 seconds, you spawn a poop cloud, which deals periodic damage to any enemies which come near it. - Gives the curse of the maze effect for the current floor. In Afterbirth dying with this trinket causes you to respawn as The Lost character and dying in a sacrifice room while holding this trinket will now unlock the Lost character. This makes it possible to use the Blood Donation machine twice from one hit of damage. See the dedicated Devil room page for more details. * item room, treasure room, item room pool, black, grey, gray, extra life, egypt, grey, gray. It stops moving while Isaac is firing tears and upon releasing the fire button, King Baby will teleport back to your location. Room icons will not show if a Curse of the Lost is in effect on the current floor. - When used will consume your current trinket, destroying it and giving you its effect permanently. +0.04 per coin is the amount added before the damage formula is calculated, as this is the only way to show a consistent amount of damage given. If you have no pickups on the ground in the current room and no other flies or spiders, Compost will spawn 1 blue fly or blue spider. If no red hearts exist, other types of hearts are consumed instead. Has a chance to drop from the Greed miniboss fight or when bombing the shopkeeper. Item Pool: Item Room, Secret Room, Key Beggar, *, grey, gray, black, face, stone, rock, baby. UNLOCK: Unlock this item by defeating Mom's Heart on hard mode as The Forgotten. Can be placed next to a pit and exploded to make a bridge. Added a new "charge bars" option in the menu, for passive items that need to be charged up before usage. There is a chance that tears that hit enemies will explode, leaving a small fire on the floor that damages enemies. When used in a room with 2 items you can choose from (e.g. After taking damage, if you have half a red heart or less, The Polaroid will give you an invincibility shield for 5 seconds. Missing Poster: Dying in a sacrifice room while holding this trinket will reveal a puzzle piece on the death screen. This item is a reference to the Tanuki suit in Super Mario 3. Can be used to open the golden door that appears in the Dark Room or the Chest. Counts as 1 of 3 angel items needed towards the Seraphim transformation. * astrology, astronomy, item room, treasure room, item room pool, blue, glow, circle, bomb. The companion will persist between rooms and floors until it dies by taking enough damage. Chance to activate increases with luck, up to around 50% chance at +20 luck. Based on the Steam Workshop mod created by Jean-Alphonse. The chance to drop hearts is affected by your luck stat and at +29 Luck it will activate 50% of the time. Item Pool: Shop, Boss Room, Challenge Room, Beggar, Demon Beggar, * dungeon room, blood challenge room, arena pool, demon beggar pool, demon judgement pool, devil beggar pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, shop room pool, shop item pool, bag, pouch. Pick up any 2 of the following items/trinkets in a single run: Complete a Chapter (floors I and II) after, Spawn three charmed enemies in the same room, Obtain 50 items in a run (duplicate passive items/familiars count towards the total, e.g., multiple, If an angel statue is broken inside the devil room the door will incorrectly be shown to be open, but can't be escaped from. UNLOCK: Unlock this item by beating Delirium on The Void floor with ???. *, black, white, grey, gray, round, circle, eye, key, hole, coin, slot, laser, Taking damage will spawn an orbital that rotates around Isaac, dealing contact damage to enemies and blocking enemy projectiles, A maximum of 3 Leprocy orbitals can be active at one time, Using the orbital to deal damage to enemies can cause it to break, Added as part of the Afterbirth+ Booster Pack #2. A familiar that can be aimed with the fire buttons similar to the Finger item, dealing contact damage to enemies equal to your tear damage. Each stat is given a multiplier that applies after all other adjustments. A baby that resembles the main character from Germination. When used, replaces all pedestal items in the current room with another random item. Black Candle removes the teleportation effect of Cursed Eye. UNLOCK: Unlock this card by beating Challenge #10 (Cursed!). Each harbinger behaves differently, based on any of the original 5 horsemen bosses, Added as part of the Afterbirth+ Booster Pack #3. UNLOCK: Unlock this item by beating Challenge #14 (It's in the Cards). These updates are known as Booster Packs. Can only happen once per room. 38 new trinkets were added in the expansion. If all enemies in the room are cleared in the order they are marked, Isaac gains a random reward from one of the following: Soul heart, Key, Pill, Bomb, Nickel, +0.2 Speed, +0.5 Range, +0.5 Tears, +1 Flat damage or +1 luck. UNLOCK: Unlock this item by playing the shell game in the arcade 100 times. When used will cut your head from your body. UNLOCK: Unlock this item by destroying 100 poops. Creates copies of pickups, even if you haven't purchased them yet. The Anemic effect will only last for the current room, but the Cube of Meat and Damage Up are both permanent. card will teleport you to the I AM ERROR room. These effects can only occur while in a hostile room with enemies. * item room, treasure room, item room pool, blood drop, red blood, drip. Item Pool: Item Room, Secret Room, brown, purple, grey, gray, * secret room pool, item room, treasure room, item room pool, +1 Health Up (The given heart container is empty), * secret room pool, item room, treasure room, item room pool, purple, pink, brown, thick odd mushroom thick. Item Pool: Item Room, Super Sloth Miniboss, Bomb Beggar, * boss rush pool, boss rush room, item room, treasure room, item room pool, bob sloth, The last door Isaac went through stays open, allowing him to leave the room even if enemies are in it. This is very similar to a Skatole for spiders instead of flies. Isaac's head will remain stationary and fire tears. * item room, treasure room, item room pool, the lost item pool, bug, yellow, face. * angel room pool, god room pool, angel room item, blue, silver, metal. in a small boss room). * item room, treasure room, item room pool, luigi board, weeja board, paper, grown. Little Gish fires tears at a rate of 1 tear per second. * item room, treasure room, item room pool, dry baby is best baby, northernlion, fat skeleton, Allows Isaac to deal contact damage to enemies for the current room. Killing the marked enemy will cause the skull to move to a different enemy. Doubles pickups and chests from clearing a room. Every time you swap Butter Bean for a different active item, it has a 10% chance to transform into the 'Wait What?' When your spacebar item is out of charge, you can press spacebar to recharge it at the cost of 2 health. UNLOCK: Unlock this item by defeating Delirium in The Void floor with Lilith. UNLOCK: Unlock this item by beating the Dark Room with Samson. Each of the 10 things spawned can be any type of consumable or sometimes a pedestal item (up to a maximum of 3 pedestal items). UNLOCK: Unlock this item by beating Satan with Eden. When used, turns Isaac invincible and gains +0.28 speed for a 5 seconds. * , the lost item pool, tong, red, bloody, lips. Bombs are effected by other passive bomb items. Upon use, gives Isaac an extra Soul heart. UNLOCK: Unlock this item by destroying 100 tinted rocks. They also retain most of your bomb synergizing items. Updated for Afterbirth! Tears now have a chance of slowing enemies and their projectiles for 2.5 seconds. Added as part of the Afterbirth+ Booster Pack #5. Can also be thrown against a door to open it (Doesn't work against Mega Satan's door). Taking this with Mom's Knife allows you to remote control the knife around the room, dealing huge damage. Renamed from "Fat Fly" to "Super Pooter". Mushroom items play their unique pickup sound. trinket (e.g. The Bean deals 5 damage, then poisons enemies for 6 total ticks of damage. Sister Maggy fires tears at a rate of 1 tear per second. UNLOCK: Unlock this item by beating Isaac in the Cathedral 5 times. Unlocked from the 'U broke it!' UNLOCK: Unlock this item by using 4 XIII - Death cards. * item room, treasure room, item room pool, DIO, dice pip, orange, brown, turban. A yellow orbital fly that will block shots and when Isaac gets hit, will seek out the nearest enemy and attack it. Isaac now also has a laser with unlimited range which fires continuously and does damage very rapidly. Tear damage is equal to Isaac's tear damage + 25 flat damage. UNLOCK: Unlock this item by beating Isaac with Cain. In Afterbirth, the beams now have improved targetting and have a high chance to spawn on top of enemies where possible. After you get hit the Stop Watch applies a slowing effect for the rest of the room to all enemies and their projectiles. Seed Total: Isaac's tears become coins and now have a 5% chance to drop pennies on the floor upon successfully hitting an enemy. Caves 2: 1 Boss Item + 2 Soul Hearts. Shot speed gives your tears more effective range, but doesn't increase your range stat directly. For example, you will now be able to use a 3 room charge item after 2 rooms instead. pink, red, eye, glow. Allows Isaac to carry two cards, runes or pills (or any combination of these) at the same time. All future stat upgrading items will now instead spread out across all other stats. UNLOCK: Unlock this item by defeating any floor after Basement I with only half a heart of health (works as The Lost). They can be distinguished from Brown Chests by their darker, purplish-brown coloring, the grayish spot on each side of the latch where the spikes will sprout from and the bloodstain. This spawns friendly charger enemies and causes Isaac to deal 2 contact damage (same as the shade did). * shop room pool, shop item pool, packet, deck, brown, orange, Allows for 2 pills to be held. * item room, treasure room, item room poolgrey, gray. with Lilith. Isaac's tears now bounce off walls and objects in the environment, such as rocks and pots. *, mtg, card, magic, gathering, green, brown, giant growth, Spawns 3 random cards on the floor when used, When used, this card will slow down enemies, Isaac's tears by -1 Shot Speed, but speed up Isaac's movement speed by +0.50 for the rest of the current room, UNLOCK: Unlock this item by getting both the Broken Watch and the Stop Watch in your collection, 48 Hour Energy - Fully recharges your active item and drops 1-2 battery pickups. UNLOCK: Unlock this item by beating Mom's Heart 4 times. A baby that resembles Twitch from Heckland. The spear cannot be thrown like Mom's Knife but deals damage while it is in contact with an enemy. Enemies will sometimes target the Mulligan if he is closer. Does not work for other pickups, such as soul hearts, nickels, dimes, cards, pills etc. Adds 0-2 coins to the payout when you use a Blood Donation machine or IV Bag. *, mr me!, Mr Meeseeks, rick and morty, brown, chest, szechuan sauce, Grants a prism orbital with a large orbital radius, Isaac's tears that pass through the prism split into four multi-colored tears, Does not deal contact damage to enemies that it passes over, Added as part of the Afterbirth+ Booster Pack #3. If the box is not empty, places all stored items and pickups in the current room. Each tick of poison damage is equal to your normal tear damage. A familiar grey spider that wanders around and allows you to see your tear damage and the health bars of all enemies. * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, shop item pool, pink, red, Item Pool: Boss Room, Challenge Room, Beggar, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, brown, bowl, grey, gray, poop, fly, Item Pool: Boss Room, Beggar, Challenge Room, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, dog, can, tin, brown, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, dog, brown, sack, bag, fly, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, carton, fly, flies, milk, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, green, bone, lump, yellow, * boss room pool, boss room item, brown, leather, bag, sack. 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